Satellites data can be used to predict natural disasters and to support emergency relief efforts. Scientific breakthroughs are challenging our assumptions and pushing our boundaries by exploring the unknown. Everyday benefits of space exploration Some examples of how space benefits Canadians and all of humanity. Topics Improving health care Experiments performed in space help us understand health problems on Earth.
Li, M. Health risks of space exploration: targeted and nontargeted oxidative injury by high-charge and high-energy particles. Redox Signal. Sridharan, D. Defining the biological effectiveness of components of High-LET track structure.
Rose, Li,Y. Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice. Datta, K. Exposure to heavy ion radiation induces persistent oxidative stress in mouse intestine.
Kumar, S. Space radiation triggers persistent stress response, increases senescent signaling, and decreases cell migration in mouse intestine. Natl Acad. USA , E—E The National Academies Press, La Tessa, C. Overview of the NASA space radiation laboratory. Schimmerling, W. Genesis of the NASA space radiation laboratory. Ozasa, K. Epidemiological studies of atomic bomb radiation at the radiation effects research foundation.
Boice, J. The past informs the future: an overview of the million worker study and the mallinckrodt chemical works cohort. Health Phys. Richardson, D. Site-specific solid cancer mortality after exposure to ionizing radiation. Epidemiology 29 , 31—40 Kamiya, K. Long-term effects of radiation exposure on health. Lancet , — Cucinotta, F. Hanahan, D. Hallmarks of cancer: the next generation.
Cell , — Barcellos-Hoff, M. Concepts and challenges in cancer risk prediction for the space radiation environment. HZE radiation non-targeted effects on the microenvironment that mediate mammary carcinogenesis. Sylvester, C. Radiation-induced cardiovascular disease: mechanisms and importance of linear energy transfer. Darby, S. Risk of ischemic heart disease in women after radiotherapy for breast cancer. Little, M. Systematic review and meta-analysis of circulatory disease from exposure to low-level ionizing radiation and estimates of potential population mortality risks.
Health Perspect. ICRP statement on tissue reactions and early and late effects of radiation in normal tissues and organs-threshold doses for tissue reactions in a radiation protection context. ICRP Publication ICRP 41 , 1— Google Scholar.
How safe is safe enough? Radiation risk for a human mission to Mars. Hughson, R. Heart in space: effect of the extraterrestrial environment on the cardiovascular system. Kreuzer, M. Low-dose ionising radiation and cardiovascular diseases-Strategies for molecular epidemiological studies in Europe. Elgart, S. Radiation exposure and mortality from cardiovascular disease and cancer in early NASA astronauts. Boerma, M. An introduction to space radiation and its effects on the cardiovascular system.
THREE , 1—12 Camacho, P. Small mammalian animal models of heart disease. Ko, K. Developing a reliable mouse model for cancer therapy-induced cardiovascular toxicity in cancer patients and survivors. Parihar, V. Cosmic radiation exposure and persistent cognitive dysfunction.
Persistent nature of alterations in cognition and neuronal circuit excitability after exposure to simulated cosmic radiation in mice.
Hinkle, J. Cranial irradiation mediated spine loss is sex-specific and complement receptor-3 dependent in male mice. Liu, B. Raber, J. Rosi, S. The final frontier: transient microglia reduction after cosmic radiation exposure mitigates cognitive impairments and modulates phagocytic activity.
Brain Circ. Kiffer, F. Behavioral effects of space radiation: a comprehensive review of animal studies. Whoolery, C. Multi-domain cognitive assessment of male mice shows space radiation is not harmful to high-level cognition and actually improves pattern separation. Mader, T. Optic disc edema, globe flattening, choroidal folds, and hyperopic shifts observed in astronauts after long-duration space flight. Ophthalmology , — Macias, B. Anterior and posterior ocular structures change during long-duration spaceflight and one year after landing.
Lee, A. Spaceflight associated neuro-ocular syndrome SANS and the neuro-ophthalmologic effects of microgravity: a review and an update.
NPJ Microgravity 6 , 1—10 Brunstetter, T. Lee, J. Head down tilt bed rest plus elevated CO 2 as a spaceflight analog: effects on cognitive and sensorimotor performance. Space flight-associated neuro-ocular syndrome. JAMA Ophthalmol. Zwart, S. Vision changes after spaceflight are related to alterations in folate- and vitamin Bdependent one-carbon metabolism. Association of genetics and B vitamin status with the magnitude of optic disc edema during day strict head-down tilt bed rest.
Patel, N. Optical coherence tomography analysis of the optic nerve head and surrounding structures in long-duration international space station astronauts. Roberts, D. Effects of spaceflight on astronaut brain structure as indicated on MRI. Van Ombergen, A. Brain ventricular volume changes induced by long-duration spaceflight. USA , — Alperin, N. Spaceflight-induced changes in white matter hyperintensity burden in astronauts. Neurology 89 , — Kramer, L. Intracranial effects of microgravity: a prospective longitudinal MRI Study.
Radiology , — Dinges, D. Stuster, J. Basner, M. Psychological and behavioral changes during confinement in a day simulated interplanetary mission to mars. Barger, L. Prevalence of sleep deficiency and use of hypnotic drugs in astronauts before, during, and after spaceflight: an observational study.
Lancet Neurol. Greene, M. Spaceflight-associated brain white matter microstructural changes and intracranial fluid redistribution. JAMA Neurol. Larson, L. Team performance in space crews: Houston, we have a teamwork problem. Smith, S. Nutritional status assessment in semiclosed environments: ground-based and space flight studies in humans. The nutritional status of astronauts is altered after long-term space flight aboard the International Space Station.
Nutritional Biochemistry of Space Flight. Nova Science Publishers, Vitamin D supplementation during Antarctic winter. Body mass changes during long-duration spaceflight. Space Environ. Human Adaptation to Spaceflight: the Role of Nutrition. Leach, C. Regulation of body fluid compartments during short-term spaceflight. Benefits for bone from resistance exercise and nutrition in long-duration spaceflight: evidence from biochemistry and densitometry.
Bone Miner. Fifty years of human space travel: implications for bone and calcium research. Sibonga, J. Adaptation of the skeletal system during long-duration spaceflight.
Holick, M. Evaluating bone loss in ISS astronauts. LeBlanc, A. Skeletal responses to space flight and the bed rest analog: a review. Neuronal Interact.
CAS Google Scholar. Schneider, V. Maheshwari, U. Comparison of fluoride balances during ambulation and bed rest. Baecker, N. Short-term high dietary calcium intake during bedrest has no effect on markers of bone turnover in healthy men.
Nutrition 26 , — Men and women in space: bone loss and kidney stone risk after long-duration spaceflight. Capacity of omega-3 fatty acids or eicosapentaenoic acid to counteract weightlessness-induced bone loss by inhibiting NF-kappaB activation: from cells to bed rest to astronauts. Heer, M. Effects of high-protein intake on bone turnover in long-term bed rest in women. Amino acid supplementation alters bone metabolism during simulated weightlessness.
Iron status and its relations with oxidative damage and bone loss during long-duration space flight on the International Space Station. Yes, of course — and I love it. Like many other kids, I used to gaze at the stars on summer evenings and dream of voyages into space. Dick or Ray Bradbury. In any case, this fascination with space exploration is helping drive great strides in our knowledge. In , an ExoMars spacecraft will be launched on a seven-month journey to the Red Planet.
The aim of the mission is to land a a rover on the surface of Mars to search for signs of past life. Moon exploration is also key, because it will serve as a forward base for human missions to deep space. Leveraging its long-standing experience in orbital infrastructures, robotics, space transportation systems and exploration, Thales Alenia Space has become a leading partner, providing 3 pressurised modules for the lunar Gateway space station.
We are also providing the backbone of the spaceship that will take the next man - and the first woman - to the Moon, while studying an innovative human landing vehicle and future solutions to guarantee a permanent human presence on the lunar surface. It certainly does! Understanding the environment on other planets where humans may one day live, and studying our own biological systems and how materials behave when not influenced by gravity, are crucially important endeavours for our future — and space exploration is helping us to find answers to our questions.
Thales Alenia Space makes the pressurised cargo modules for all Cygnus vessels. It will lead to an massive data harvest that will feed scientists' research for many years to come.
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